Principle of hyaluronidasis :

Hyaluronidase (or hyalase) is an enzyme that dissolves hyaluronic acid, active even on injections that were several years ago. It is not active on certain hyaluronic acids such as Scupltra® or Radiesse® or on old silicone injections.

  • Hyaluronidase injections can correct
  • Overcorrection
  • Subcutaneous nodule
  • Tyndall effect: bluish coloring related to the visibility by transparency of a product injected slightly superficially under thin skin
  • Asymmetry
  • Correction technically satisfactory but for which the patient wishes, after reflection, not to wait several months for the product to resorb


Only doctors, with a practice authorization, can inject hyaluronidase in Switzerland. The laboratories selling it are only authorized to sell it to doctors with a license. There are many counterfeits that can endanger your body.


Skin allergy test: for patients who have never had an injection of hyaluronidase or for multi-allergic patients, a small dose of hyaluronidase is injected in the arm and one waits 20-30 minutes before injecting the desired site. Redness appearing within 5 minutes and persisting at 20 minutes is considered a positive reaction and contraindicates an injection.
Topical anesthesia with cream and injection with cannula or needle.


Time to results: 4 to 10 days (1 injection is sufficient most of the time)
Longevity of results: definitive

Before injfection:

Inform Dr. Lucas of any anticoagulant medication (Sintrom, Coumadin, Eliquis, etc..) or Aspirin, special care will be taken during injections to avoid small vessels and prevent hematomas and for some injections, a relay will be organized if medically possible.
Take Arnica capsules 5 times a day for 5 days before surgery if prone to hematoma.
Contraindications: pregnancy, breastfeeding, hyaluronidase allergy

Procedure :

Pain: the pain during the procedure is not significant, with an adapted anesthesia, but patients describe a burning discomfort during the hyaluronidase injection
Duration of the procedure: 20 minutes
Anesthesia: local or topical
Location: office
Outpatient (without hospitalization)

After the procedure:

Post-injection pain: no
Social eviction: no (except if hematoma, which can be minimized with the use of a cannula and minimal swelling between 1 and 3 days depending on the patient)
Return to work: immediate
Return to sport: immediate

Avoid anti-inflammatory drugs and smoking for 48 hours
Ice for 48 hours to reduce swelling
Massage areas the next day if you feel irregularities or hard areas for 1 week
Arnica capsules 5 capsules 5 times a day for 5 days after injection if hematoma
Control Dr Lucas 2 weeks


– Infection, hematoma, asymmetry, undercorrection
– Allergy: the allergic risk is low, but it must always be taken into account and requires strict precautions.


Hyaluronidasis nose, nasolabial folds, chin, jawline and lips